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新生儿缺氧缺血性脑损伤后神经发生研究进展

Jun-jie LU,Li JIAN,Li HUANG

International Journal of Pediatrics（2008）

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Abstract
新生儿缺氧缺血性脑损伤后激活神经生发区的神经干细胞,发生增殖、分化、迁移.生发区缺氧缺血后,触发基因转录,启动下游信号分子传导,神经发生.缺氧缺血性脑损伤后,影响神经发生的因素有神经生长因子、神经递质、细胞因子等.神经发生可以改善新生儿缺氧缺血性脑损伤后的功能恢复.
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Key words
neurogenesis,brain injury,hypoxic-ischemic
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