Rapid diagnosis for 3570 cases with genital candidiasis by CHROMagar

Objective\r\nTo identify the pathogen of genital candidiasis by CHROMagar and analyze the resistance status of antifungals.\r\n\r\n\r\nMethods\r\nAdminister direct microscopy examination and CHROMagar culture after sampling from 3507 cases of genital candidiasis; then proceed the in vitro sensitivity analysis of antifungals for 2172 strains of Candida.\r\n\r\n\r\nResults\r\nHyphae and spores were detected from 1332 cases(1332/3507).2172 strains of Candida were isolated by CHROMagar culture(2172/3507),in which there were 1786 strains of Candida albicans(1786/2172),while 350 strains of non-Candida albicans in female vaginal discharge(350/1347).In vitro sensitivity analysis of the antifungal drugs showed none resistance to amphotericin B and different degrees of resistance to azole antifungals and nystatin.\r\n\r\n\r\nConclusion\r\nCHROMagar culture is a useful and rapid diagnostic method for genital candidiasis.Genital candidiasis in local area is mainly caused by Candida albicans,while there wereincreasing portion of vulvovaginal candidiasis caused by non-Candida albicans.In vitro sensitivity analysis of the antifungal drugs showed different degrees of resistance to azole antifungals.\r\n\r\n\r\nKey words: \r\nCandidiasis; CHROMagar; Drug tolerance