Effect Of Detection Of Epigenomic Changes In Plasma-Derived Cell-Free Dna On Multicancer Classification.

Anna Bergamaschi,David Haan,Jeremy Ku,Yuhong Ning,Chris Ellison,Gulfem Guler,Tierney Phillips,Erin McCarthy,Michael Antoine,Albert Nguyen,Aaron Scott,Paul Lloyd,Alan Ashworth,Kelly Bethel,Samuel Levy

JOURNAL OF CLINICAL ONCOLOGY（2020）

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摘要

1539Background: Epigenomic changes in DNA methylation patterns are more precisely delineated by active demethylation events as marked by 5-hydroxymethylation (5hmC) of cytosine residues. 5hmC appea...

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