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SET/CAN和DEK/CAN融合基因阳性急性髓系白血病一例并文献复习

Yu Shi

Journal of Leukemia and Lymphoma（2017）

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Abstract
目的 提高对SET/CAN和DEK/CAN融合基因阳性急性髓系白血病(AML)诊治的认识.方法 对1例SET/CAN和DEK/CAN融合基因阳性AML患者的临床特点进行分析,并结合相关文献进行复习.结果 该例SET/CAN和DEK/CAN融合基因阳性AML患者以发热起病,化疗2个周期后获得完全缓解,但很快复发,生存期仅8个月.结论 SET/CAN和DEK/CAN融合基因阳性AML患者罕见,生存期短,预后较差,对化疗不敏感.
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Key words
acute myeloid leukemia,fusion genes,dek/can
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