急性嗜碱性粒细胞白血病一例并文献复习

Journal of Leukemia and Lymphoma(2017)

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Abstract
目的:探讨急性嗜碱性粒细胞白血病(ABL)的诊断、治疗及预后。方法回顾性分析1例72岁确诊为ABL的1q染色体异常的老年女性患者临床资料并进行相关文献复习。结果该患者经骨髓象、甲苯胺蓝染色、免疫分型、染色体等检查诊断为ABL,经化疗联合抗组胺药物治疗后效果不佳。结论诊断ABL主要依据于骨髓及外周血嗜碱性粒细胞明显增多、无Ph染色体异常、骨髓甲苯胺蓝染色阳性等特点;ABL尚无满意的治疗方法,通常采用化疗联合抗组胺药物治疗,但治疗效果差、死亡率高、预后不佳。
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acute basophilic leukemia
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