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Interim Subgroup Analysis For Response By Pd-L1 Status Of Classical-Lung, A Phase Ib/Ii Study Of Pepinemab (Vx15/2503) In Combination With Avelumab In Advanced Nsclc.

Michael Rahman Shafique,Terrence Lee Fisher,Elizabeth E. Evans,John E. Leonard,Desa Rae Electa Pastore,Crystal L. Mallow,Ernest Smith,Andreas Schröder,Kevin M. Chin,Joseph Thaddeus Beck,Megan Ann Baumgart,Ramaswamy Govindan,Nashat Y. Gabrail,Rachel E. Sanborn,Alexander I. Spira,Nagashree Seetharamu,Yanyan Lou,Aaron Scott Mansfield,Jonathan Wade Goldman,Maurice Zauderer

JOURNAL OF CLINICAL ONCOLOGY（2020）

Cited 2|Views52
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Abstract
3011Background: Antibody blockade of semaphorin 4D (SEMA4D, CD100) promotes tumoral dendritic cell and CD8+ T cell infiltration and reduces function and recruitment of immunosuppressive myeloid cel...
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Key words
pepinemab,interim subgroup analysis,advanced nsclc,classical-lung
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