羊膜移植对兔角膜碱烧伤后局部白介素-6分泌的影响

Chinese Journal of Optometry & Ophthalmology(2005)

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Abstract
目的观察羊膜移植对兔角膜碱烧伤后泪液中白介素-6(interleukin-6,IL-6)分泌的影响.方法制作30只新西兰白兔角膜碱烧伤模型,分为羊膜移植组(20只)与对照组(10只).术后3周内每3日1次分别检测两组兔泪液中IL-6的含量.结果①烧伤后24 h内,两组兔泪液中IL-6的水平相似.②此后羊膜移植组泪液中IL-6水平略有升高,1周后开始降低,第21天时基本测不出;而对照组持续升高,第21天时仍保持较高的水平.结论羊膜移植可有效抑制局部炎症细胞IL-6的释放,在角膜碱烧伤后的抗炎治疗方面具有重要的临床意义.
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Key words
amniotic membrane transplantation,alkali
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