索利那新联合PCEA技术防治前列腺术后膀胱痉挛性疼痛的临床研究
International Medicine and Health Guidance News(2012)
Abstract
[目的]探讨耻骨上前列腺摘除术后,采用索利那新联合硬膜外自控镇痛(PCEA)技术防治膀胱痉挛性疼痛的效果.[方法]将50例行耻骨上前列腺摘除术患者随机分为试验组和对照组各25例.对照组患者术后给予PCEA 3天,试验组在此基础上于术前1天起口服索利那新片5 mg,每天1次,至术后第7天.观察两组患者术后3天内膀胱痉挛率、膀胱冲洗时间及药物不良反应情况.[结果]试验组膀胱痉挛痛率为20%,对照组为48%;试验组膀胱冲洗时间为(2.55±0.90)天,对照组为(3.76±0.64)天;试验组膀胱痉挛痛率、膀胱冲洗时间均显著低于对照组(P<0.05).药物不良反应无显著差异.[结论]索利那新联合PCEA技术能更好地防治前列腺术后膀胱痉挛性疼痛,可于基层医院推广应用.
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Key words
solifenacin succinate,epidural analgesia,cystospasm,patient-controlled
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