Expression of COX-2 mRNA in rat aortic endothelial cells in high glucose environment
Chinese Journal of Endocrinology and Metabolism(2009)
Abstract
The expression of cyclooxy genase-2 (Cox-2) in endothelial cells (ECs) was determined. These cells were from aorta of diabetic rat and SD rats, cultured in vitro with high glucose. High glucose increased COX-2 mRNA expression both in rat aortic ECs cultured in vitro and in vivo,which was inhibited by aspirin treatment.\r\n\r\nKey words: \r\nAorta; Endothelial cells; High glucose; COX-2 ; Aspirin
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Key words
Prostaglandin E2
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