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MicroRNA-21与支气管哮喘

Yaqin Xu

International Journal of Pediatrics（2018）

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Abstract
MicroRNA是一类进化上高度保守的单链小分子RNA,参与调控机体生长、发育、代谢以及疾病的发生.最近研究表明,一部分MicroRNA在过敏性炎症特别是支气管哮喘的发病过程中起重要作用.研究microRNA-21在哮喘发病中的调节机制,可帮助寻找安全、高效、特异的治疗方法.该文就miR-NA-21与支气管哮喘发病机制相关作用予以综述.
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Key words
Bronchial asthma,MicroRNA,Airway remodeling
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