Sexual and Urinary Disorders after Treatment of Rectal Cancer by Radiotherapy and Surgery at the Dantec University Hospital of Dakar

We\r\nperformed a descriptive retrospective study of sexual and urinary disorders\r\nafter treatment of rectal cancer by radiotherapy and/or surgery at the Dantec\r\nUniversity Hospital in Dakar from 2008 to 2015. The objective of the study was\r\nto evaluate these sexual and urinary complications and the factors influencing\r\nit. We have collected 50 patients. The average age of is 55.7 years with a sex\r\nratio of 0.78. The dominant clinical signs are rectorrhagia (66.0%). Endoscopy\r\n(94.0% of patients) showed an ulcerative-budding appearance in 84.0% of cases.\r\nThe preferred location was the lower rectum 66.0%). The predominant histologic\r\ntype is adenocarcinoma lieberkunien (82.0%). Computed tomography is performed\r\nin 78% of cases and MRI in 30%. Stage III accounts for 70.0% of cases.\r\nThirty-two patients (64.0%) were treated with conventional 2-beam 2D radiation\r\ntherapy with or without chemotherapy. The total dose of 46 Gy in 23 sessions\r\nwas the most used, found in 22 patients; 30 Gy in 10 sessions in 9 cases. And\r\n16 Gy in 10 sessions, found in 1 case. Surgery performed was abdominoperineal\r\namputation (58.0%) and conservative surgery (42.0%). We note a complete\r\nresponse in 28.0% of patients; 8.0%, an increase of 16.0% and a stabilization\r\nof 4.0%. The sexual disorders are more important after radiotherapy compared to\r\nnon-irradiated patients: 31.3% vs 5.6% (p = 0.035). We observe respectively\r\nthat 2%, 6% and 8% of our patients had urinary disorders in the form of acute\r\nretention, urinary incontinence, and urinary burning. Patient follow-up time\r\nwas between 0 and 42.83 months with an estimated average of 34.9 ± 3.37. The evolution is\r\nmarked at 6 months by a persistence of sexual disorders in 63.8% of cases and\r\nurinary dysfunction in 4% of cases.