Research letterInactivation of the glucose transport system in sporulating yeast

The glucose transport system of Saccharomyces cerevisiae was inactivated during sporulation. The glucose uptake capacity of a culture (measured with xylose as substrate) decreased to 50% when about 15% of the population was transformed into asci. At the end of sporulation the residual transport capacity was about 20% of the initial one. No changes in glucose transport were observed in a non-sporulating diploid treated in the same conditions. Reappearance of the transport did not occur during germination if this was inhibited by cycloheximide.