Comprehensive characterization of biocomposite surface based on the mesoporous silica and lysozyme molecules: Chemistry, morphology, topography, texture and micro-nanostructure

•Analysis of morphology, micro and nanostructure of biocomposite LYS/MCF surface.•Weakening of hydrogen bonds in the secondary structure upon protein adsorption.•Diminishing of pore sizes by LYS molecules packed inside the pores (XRD, AFM).•Homogenous distribution of C, O, N, S on the protein/silica surface (EDX mappings).•MCF-LYS interactions clearly seen on XPS spectra.