Aberrant Neural Computation of Uncertainty Predicts Cocaine Use Relapse
Biological Psychiatry(2020)
摘要
Substance use disorders (SUD) have long been associated with risky decision-making. This behavior could be motivated by 1) increased risk preference (but intact encoding of risk per se), and 2) inability to estimate the uncertainty of action-outcome associations. While the former has been extensively investigated, the latter has not received sufficient attention.
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关键词
Cocaine Relapse,Computational Psychiatry,Bayesian Modeling,Uncertainty,fMRI
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