Genomic characterization of malignant pleural mesothelioma and associated clinical outcomes.
Cancer treatment and research communications(2020)
摘要
Our study has identified that TP53 confers worse survival and response to platinum chemotherapy compared to BAP1. Overall PDL1 expression and TMB is low in patients with MPM resulting in limited benefit from single agent PD-1/PD-L1 agent.
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关键词
Genomic,Mesothelioma,Mutation burden
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