Congenital chagas disease: Development and assessment of a specific IgM capture-based assay for diagnosis of transmission

Acta Tropica(2021)

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摘要
•The ELISA technique developed was based on the capture of specific anti-Trypanosoma cruzi IgM antibodies and able to detect them accurately on infected newborns samples.Remarkable performance has been achieved using the new CP4 chimeric recombinant antigen.•This technique can certainly improve the diagnosis of connatal infection for Chagas disease.
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关键词
Congenital,Chagas Disease,Diagnosis,IgM,capture assay
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