Six flavonoids inhibit the antigenicity of β-lactoglobulin by noncovalent interactions: A spectroscopic and molecular docking study

•Six flavonoids reduced the antigenicity of β-LG by noncovalent interaction.•Structures of β-LG experienced distinct changes due to noncovalent interaction.•We explored the binding patterns of flavonoids and β-LG by molecular docking.•The flavonoids bound to the epitope regions of β-sheet and β-turn in β-LG.