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Expression of Heat shock protein 70 (Hsp70-1) in Plasmodium berghei ookinetes and its participation in midgut mosquito infection

Maria Carmen Rodriguez,Jesús Martínez-Barnetche,Alba N Lecona-Valera,Juan Téllez-Sosa,Rocio S Argotte-Ramos,Alejandro Alvarado-Delgado, Marbella T Ovilla,Vianey Saldaña-Navor,Mario H Rodriguez

Molecular and Biochemical Parasitology（2020）

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Abstract
•Several Hspt proteins are present in Plasmodium berghei sexual stages, but only PbHsp70-1 is expressed in ookinetes.•PbHsp70-1 was localized in micronemes and on the surface of ookinetes.•PbHsp70-1 participates in Plasmodium berghei sexual stages development and in the midgut infection of Anopheles albimanus.
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Key words
Plasmodium ookinetes,Heat shock protein70 (Hsp70-1),Micronemes
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