Feasibility Of Beans/Bran Enriching Nutritional Eating For Intestinal Health & Cancer Including Activity For Longevity: A Pilot Trial To Improve Healthy Lifestyles Among Individuals At High Risk For Colorectal Cancer

Purpose:Examine the feasibility and preliminary effects of a lifestyle intervention of rice bran plus navy bean supplementation, and physical activity (PA) education on intake of fiber and whole grains, and PA levels.Design:Randomized-controlled, single-blinded.Setting:Academic institution and free-living.Subjects:Adults >18 years, with >= 1 adenomatous polyp removed within 3 years.Intervention:Participants received powder and pre-prepared meals and snacks that contained either rice bran (30 g/day) plus navy bean (30 g/day), or Fibersol-2(R) (10 g/day), for 12-weeks. All participants received a 1-hour (PA) education session.Measures:Feasibility was assessed by recruitment and retention rates, and compliance to the study foods and procedures. Three-day food logs were analyzed using Nutritionist Pro (TM) to estimate fiber intake, and the Automated Self-Administered 24-hour (ASA24(R)) Dietary Assessment Tool calculated Healthy Eating Index (HEI) whole grain and total scores. PA was measured using an ActivPAL (TM) accelerometer.Analysis:Continuous data were summarized as median, range, and percent change from baseline to post-intervention.Results:N = 20 (86.9%) completed the intervention. Compliance was 92% in the rice bran plus navy bean versus 89% in Fibersol-2(R). Navy bean consumption increased from 2 g/day to 30 g/day, and rice bran from 0 g/day to 30 g/day. Fiber intake (g/day) increased by 73% versus 82%, HEI whole grain improved by 270% versus 37%, and HEI total improved by 10% versus 9.1% in rice bran plus navy bean and Fibersol-2(R), respectively. Total PA (MET-hours/day) showed minimal change for intervention (+0.04%) and control (+4%).Conclusion:Findings merit a larger trial of rice bran plus navy bean and PA to evaluate efficacy for dietary and cancer prevention-related outcomes.