Semi supervised segmentation and graph-based tracking of 3D nuclei in time-lapse microscopy

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in accurate boundaries when the training data is weakly annotated. Towards this, a 3DU-Net is trained to get the centroid of the nuclei and integrated with a simple li...