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A bifunctional DNA probe for sensing pH and microRNA using a nanopore.

Yun Zhang,Peng Song,Bingyuan Guo,Wenying Hao,Lei Liu,Hai-Chen Wu

ANALYST（2020）

Cited 3|Views17
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Abstract
We have developed a bifunctional probe based on triplex molecular beacons for the measurement of environmental pH and quantification of microRNA-10b using a nanopore. The probe responds sharply to solution pH changes in the range of 6.0-7.5. The limit of detection for microRNA-10b is as low as 5.0 pM.
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Key words
bifunctional dna probe,microrna,ph
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