When to Rule Out COVID 19: How Many Negative RT PCR Tests Are Needed?
Respiratory Medicine Case Reports(2020)
摘要
Amidst the COVID-19 pandemic, clinicians have been plagued with dilemmas related to the uncertainty about diagnostic testing for the virus. It has become commonplace for a patient under investigation (PUI) to repeatedly test negative but have imaging findings that are consistent with COVID-19. This raises the question of when the treating team should entertain alternative diagnoses. We present such a case to help provide a framework for how to weigh repeatedly negative test results in clinical decision making when there is ongoing concern for COVID-19.
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关键词
COVID-19 infection,RT-PCR,CT Chest,Sensitivity,Specificity,Prevalence,Negative predictive value,False negative rate
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