The study of myocardial ischemia-reperfusion treatment through computational modelling
Journal of Theoretical Biology(2021)
Abstract
•The mechanism of ischemia-reperfusion treatment is studied using an oxygen model.•Electro-oxygen model is used to observe the myocardial damage region.•Oxygen exceeds 1.0 (optimum) at early reperfusion increases reperfusion-injury risk.•Risk increases for the case of long ischemia-reperfusion time and >80% early oxygen.•From its conductivity result, the injury region is limited within the ischemic area.
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Key words
Myocardial infarction,Ischemia,Ischemia-reperfusion,Ischemic injury,Electrophysiology
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