Antibody-dependent enhancement of coronavirus

•Five mechanisms of antibody-dependent enhancement have been discussed to date, with the most frequent effect being related to FcγR.•Antibody-dependent enhancement has been discovered in both severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus, but the mechanism is not completely clear; different studies have led to different opinions.•Many scientist have mentioned the potential existence of antibody-dependent enhancement in the 2019 novel coronavirus – severe acute respiratory syndrome coronavirus 2.•The most recent studies on both convalescent plasma transmission and the application of inactivated vaccine did not report any case of antibody-dependent enhancement.