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Critically Ill Covid-19 Patients Attended By Anesthesiologists In Northwestern Spain: A Multicenter Prospective Observational Study

M Taboada,P Rama, R Pita-Romero,E Moreno,S Leal,M Varela,M Cid,V Caruezo, S Alvarado de la Torre,M Corujeira,A Sarmiento,B Domínguez,P Diaz, L Cánovas,M López Sánchez, E Vilas, A Rodríguez,L Freire, S Domínguez,A Baluja,P G Atanassoff

REVISTA ESPANOLA DE ANESTESIOLOGIA Y REANIMACION(2021)

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摘要
Background and objectives: There are limited information on outcome, complications and treatments of critically ill COVID-19 patients requiring admission to an intensive care unit (ICU). The aim of this study is to describe the clinical ICU course, treatments used, complications and outcomes, of critically COVID-19 patients admitted in seven ICU in Galicia region during the 2020 March-April pandemic peak.Methods: Between March 21 and April 19, 2020, we evaluated critically COVID-19 patients admitted to the ICU of Anesthesia of seven hospitals in Galicia, northwestern Spain. Outcome, complications, and treatments were monitored until May 6, 2020, the final date of follow-up.Results: A total of 97 critically ill COVID-19 patients were included. During ICU stay, mechanical ventilation became necessary in 80 (82.5%) patients, and tracheostomy in 22 (22.7%) patients. Prone position was used frequently in both intubated (67.5%) and awake (27.8%) patients. Medications consisted of antivirals agents (92.7%), corticosteroids (93.8%), tocilizumab (57.7%), and intermediate or high doses of anticoagulants (83.5%). The most frequent complications were ICU-acquired infection (52.6%), thrombosis events (16.5%), and reintubation (9.3%). After a median follow-up of 42 (34-45) days, 15 patients (15.5%) deceased, 73 patients (75.2%) had been discharged from ICU, and nine patients (9.3%) were still in the ICU.Conclusions: A high proportion of our critically ill COVID-19 patients required mechanical ventilation, prone positioning, antiviral medication, corticosteroids, and anticoagulants. ICU complications were frequent, mainly infections and thrombotic events. We had a relatively low mortality of 15,5%. (C) 2020 Sociedad Espanola de Anestesiologia. Reanimacion y Terapeutica del Dolor. Published by Elsevier Espana, S.L.U. All rights reserved.
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关键词
CON/ID-19, SARS-CoV-2, Critically ill patients, Acute respiratory distress syrldrorne (ARDS), Prone positioning, Corticosteroids
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