Hrp2/3 Mutation In Recrudescent Plasmodium Falciparum Malaria Case Acquired In Ethiopia

Shiraz Gefen-Halevi, Valentin Belinson,Uri Manor,Zeala Gazit,Gill Smollan,Natasha Belausov,Asaf Biber,Eli Schwartz,Tamar Grossman,Eyal Leshem,Sharon Amit

JOURNAL OF TRAVEL MEDICINE（2021）

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摘要

A 65-year-old Israeli working in Welkait, Ethiopia, not using malaria prophylaxis, developed fever. Malaria RDT was consistent with non-falciparum malaria (plasmodium LDH+/HRP-) but microscopy showed typical P. falciparum. HRP2/3 were negative by PCR. The patient suffered two recrudescence episodes following artemether-lumefantrine and atovaquone-proguanil treatments, and responded to mefloquine treatment.

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关键词

Malaria, P. falciparum, HRP2/3 mutation, Recrudescent, Ethiopia

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