Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions

Anna Borgström,Barbara Hauert,Sven Kappel,Eugenio Zoni,Mirjam Kiener,Paulina Stokłosa,Roland Baur,Martin Spahn,Marianna Kruithof-de Julio,Christine Peinelt

Journal of Molecular Biology（2021）

引用 16|浏览31

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摘要

Transient receptor potential melastatin 4 (TRPM4) is a broadly expressed Ca2+ activated monovalent cation channel that contributes to the pathophysiology of several diseases.

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关键词

patch-clamp,small molecule inhibitors,adhesion,proliferation,migration

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