Identification of NLR-associated Amyloid Signaling Motifs in Bacterial Genomes

Witold Dyrka,Virginie Coustou,Asen Daskalov,Alons Lends,Thierry Bardin,Mélanie Berbon,Brice Kauffmann,Corinne Blancard,Bénédicte Salin,Antoine Loquet,Sven J Saupe

Journal of Molecular Biology（2020）

引用 16|浏览22

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摘要

•Bacterial genomes contain amyloid motifs associated to homologs of Nod-like receptors.•Bacterial amyloid signaling sequences (BASS) occur mainly in multicellular bacteria.•Selected BASS-motifs propagate as prions in a fungal model.•BASS3 motifs cross-seed in vivo with RHIM and fungal PP-motifs.

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关键词

signal transduction,programmed cell death,actinobacteria,cyanobacteria,multicellularity

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