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Making the invisible enemy visible

Tristan I. Croll,Kay Diederichs,Florens Fischer,Cameron D. Fyfe,Yunyun Gao,Sam Horrell,Agnel Praveen Joseph,Luise Kandler,Oliver Kippes,Ferdinand Kirsten,Konstantin Müller,Kristopher Nolte,Alexander M. Payne,Matthew Reeves,Jane S. Richardson,Gianluca Santoni,Sabrina Stäb,Dale E. Tronrud,Lea C. von Soosten,Christopher J. Williams,Andrea Thorn

Nature Structural & Molecular Biology（2021）

Cited 10|Views30
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Abstract
Structural biology plays a crucial role in the fight against COVID-19, permitting us to ‘see’ and understand SARS-CoV-2. However, the macromolecular structures of SARS-CoV-2 proteins that were solved with great speed and urgency can contain errors that may hinder drug design. The Coronavirus Structural Task Force has been working behind the scenes to evaluate and improve these structures, making the results freely available at https://insidecorona.net/.
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Key words
Databases,Drug discovery,Electron microscopy,Molecular modelling,X-ray crystallography,Life Sciences,general,Biochemistry,Protein Structure,Membrane Biology,Biological Microscopy
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