Changes in audiometric threshold and frequency selectivity correlate with cochlear histopathology in macaque monkeys with permanent noise-induced hearing loss

Hearing Research(2020)

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摘要
•Monkeys exposed to high level noise showed broadened perceptual auditory filters.•Auditory filter width and audiometric threshold changes were exponentially related.•Audiometric thresholds and filter widths were explained primarily by outer hair cell loss.•Interactions between cochlear histological components explained additional variability.•First within-subject study of cochlear anatomy and perceptual filters after noise exposure.
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关键词
Frequency selectivity,Sensorineural hearing loss,Noise exposure,Nonhuman primate,Auditory filters,ERB
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