Colocalization of tracks from boron neutron capture reactions and images of isolated cells.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine(2020)
摘要
In Boron Neutron Capture Therapy, the boronated drug plays a leading role in delivering a lethal dose to the tumour. The effectiveness depends on the boron macroscopic concentration and on its distribution at sub-cellular level. This work shows a way to colocalize alpha particles and lithium ions tracks with cells. A neutron autoradiography technique is used, which combines images of cells with images of tracks produced in a solid-state nuclear track detector.
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