Upregulation of JHDM1D-AS1 alleviates neuroinflammation and neuronal injury via targeting miR-101-3p-DUSP1 in spinal cord after brachial plexus injury

•LncRNA JHDM1D-AS1 and DUSP1 are downregulated in the spinal cord after tBPI while miR-101-3p is upregulated.•Overexpression of lncRNA JHDM1D-AS1 suppresses neuronal apoptosis and microglial inflammation.•LncRNA JHDM1D-AS1 exerts neuroprotective and anti-inflammatory effects via sponging miR-101-3p.•LncRNA JHDM1D-AS1 regulates DUSP1 mediated p38 and NF-κB pathway activation through repressing miR-101-3p.