Clinical Significance of Renal Function Indicators in Urine of Henoch-Schonlein Purpura Nephritis Children
MEDICAL MATERIALS AND ENGINEERING(2012)
Abstract
In this study, we analyzed the relationship of renal function indicators in urine and changes of renal function in children patients with Henoch-Schonlein purpura nephritis (HSPN). The information of 62 patients and 30 healthy ones were retrospectively reviewed and compared, the concentration of urinary beta 2-micro globulin, urinary retinol-binding protein, urinary mALB, urinary transferrin ferritin, urinary alpha 1-MG, urinary creatinine N-acety1-beta-D-glucosaminidase were determined by full-automatic biochemistry analyzer. The level of beta 2-MG, RBP, urinary mALB, NAG, uTF and alpha 1-MG in children with HSPN were all higher than those in control group, in which except the RBP and NAG, others all have statistical significance (P<0.05). beta 2-MG and uTF were obvious abnormal with the rate of 67.74% and 62.90% respectively. The determination of above indexes was significant for early monitoring of kidney damage in children with HSPN and early intervention to prevent the progression of disease.
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Key words
Henoch-schonlein purpura nephritis,Renal function,Micro globulin,Children
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