Preparation on Sustained-Release Drug of Na-MMT-Miglitol

In order to sucessfully prepare Na-MMT-Miglitol composite, the adsorption effect factors of the different concentrations, temperature, pH and time for miglitol were investigated respectively. By means of the adsorption capacity changes of Na-MMT, the maximum adsorption capacity of Na-MMT as the experimental conditions to prepare the sustained-release drug of Na-MMT-Miglitol, in addition, the Na-MMT-Miglitol was characterized by Fourier Transform infrared Absorption Spectrum (FTlR) and Scanning Electron Microscopy (SEM). The results show that the adsorption capacity of Na-MMT can reach maximum adsorption when the experimental conditions of the initial concentration of miglitol 5mmol / L, temperature 40 degrees C, pH 2 and the adsorption time 1.5h were selected. the characterization results of FTIR and SEM can infer that miglitol and Na-MMT are reacted to prepare Na-MMT-Miglitol composite successfully.