Optimized Sample Preparation and Data Processing of Data-Independent Acquisition Methods for the Robust Quantification of Trace-Level Host Cell Protein Impurities in Antibody Drug Products.
Journal of Proteome Research（2020）
Key words
host cell proteins (HCPs),data-independent acquisition (DIA),protein quantification,sample preparation,data validation,therapeutic mAbs,adalimumab,bevacizumab,nivolumab,trastuzumab
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