Interaction of Autotaxin With Lipoprotein(a) in Patients With Calcific Aortic Valve Stenosis

Raphaëlle Bourgeois,Romain Devillers,Nicolas Perrot,Audrey-Anne Després,Marie-Chloé Boulanger,Patricia L Mitchell,Jakie Guertin, Patrick Couture,Michael B Boffa,Corey A Scipione,Philippe Pibarot,Marlys L Koschinsky, Patrick Mathieu,Benoit J Arsenault

JACC: Basic to Translational Science（2020）

引用 15|浏览5

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摘要

•Lipoprotein(a) is an important carrier of autotaxin and lysophosphatidic acid in the bloodstream.•Autotaxin might physically interact with apolipoprotein(a).•The plasma concentration of autotaxin transported by lipoprotein(a) may be an important predictor of calcific aortic valve stenosis.

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关键词

autotaxin,calcific aortic valve stenosis,lipoprotein(a),low-density lipoproteins,obesity

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