Transmitting the Signal: Structure of the β1-Adrenergic Receptor-Gs Protein Complex
Molecular Cell（2020）
摘要
In this issue of Molecular Cell, Su et al. (2020) report a cryo-EM structure of the beta 1-adrenergic receptor (beta 1AR) in complex with a heterotrimeric Gs protein, which offers novel insights into receptor activation and provides a structural framework to better understand the transducer-coupling mechanism for adrenergic receptors.
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