Changes in peripheral immune cells after intraoperative radiation therapy in low-risk breast cancer.

Isabel Linares-Galiana,Miguel Angel Berenguer-Frances,Rut Cañas-Cortés,Monica Pujol-Canadell, Silvia Comas-Antón,Evelyn Martínez,Maria Laplana,Héctor Pérez-Montero,María Jesús Pla-Farnós,Arturo Navarro-Martin,Miriam Nuñez,Brigitte Both,Ferran Guedea

Journal of Radiation Research（2020）

引用 16|浏览6

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摘要

A detailed understanding of the interactions and the best dose-fractionation scheme of radiation to maximize antitumor immunity have not been fully established. In this study, the effect on the host immune system of a single dose of 20 Gy through intraoperative radiation therapy (IORT) on the surgical bed in low-risk breast cancer patients undergoing conserving breast cancer has been assessed. Per...

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关键词

immune system,immunomodulation,flow cytometry,immunophenotyping,breast cancer,intraoperative radiation therapy

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