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[Preliminary Study on the Secretory Performance of Mycobacterium tuberculosis Hypoxic Response Protein 1 (Rv2626c)].

Wen-Yi Ni,Tao Luo,Peng-Jiao Ma,Liang Ge,Rong-Chuan Zhao,Xin-Yan Wang,Zong-Hai Chen,Wei Liao,Lang Bao

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition（2020）

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Abstract
OBJECTIVE:To verify the secretory ability of the hypoxic response protein 1 (HRP1) encoded by Mycobacterium tuberculosisRvcMETHODS:The target gene attached with His tag was amplified from the genome of Mtb standard virulence strain H37Rv. The recombinant plasmid contained the above amplified product was constructed and electroporated into Mycobacterium smegmatis2RESULTS:The HRPGroELCFPCFPCONCLUSION:The protein HRP1 encoded by Mtb Rvc
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Key words
Dormancy,HRP1,Mycobacterium tuberculosis,Secreted protein
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