SH3KBP1 scaffolds endoplasmic reticulum and controls skeletal myofibers architecture and integrity
biorxiv(2020)
Abstract
Altogether our results identify SH3KBP1 as a new regulator of myonuclear domains establishment in the early phase of muscle fibers formation through ER scaffolding and later in myofibers integrity through T-tubules scaffolding/maintenance.
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Key words
skeletal myofibers architecture,endoplasmic reticulum
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