Ursolic acid inhibits cell migration and promotes JNK-dependent lysosomal associated cell death in Glioblastoma multiforme cells

Gillian E. Conway,Deimante Zizyte,Julie Rose Mae Mondala,Zhonglei He,Lorna Lynam,Mathilde Lecourt,Carlos Barcia,Orla Howe,James F Curtin

biorxiv（2020）

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摘要

Collectively, our data identifies that UA rapidly induces a lysosomal associated mechanism of cell death in addition to UA acting as an inhibitor of GBM cell migration.

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关键词

Ursolic acid,cancer,therapeutics,cell death,migration,nutraceutical,cell signalling

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