Weight and organ specific immune cell profiling of sleeve gastrectomy in mice

David A. Harris,Renuka Subramaniam,Todd Brenner,Ali Tavakkoli,Eric G. Sheu

biorxiv（2021）

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摘要

•SG induces a weight-loss independent metabolic and immunologic phenotype.•SG increases innate-like B cells, neutrophils, M2 macrophages, and circulating immunoglobulins.•Changes in cellular immunity after SG may affect glucose metabolism.

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关键词

SG,T2D,TNF-α,VAT,POD,GLP-1,OGTT,ITT,DIO,CyTOF,ARG1,TGR5,RYGB

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