Ubiquitination and Phosphorylation are Independently Required for Epsin-Mediated Internalization of Cargo in S. cerevisiae

Arpita Sen,Wen-Chieh Hsieh,Claudia B. Hanna,Chuan-Chih Hsu,McKeith Pearson,W. Andy Tao,R. Claudio Aguilar

biorxiv（2020）

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摘要

We propose a model in which a dual detection mechanism is used by Ub-binding elements of the sorting machinery to differentiate among multiple Ub-cargoes.

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关键词

Endocytosis,internalization,Ena1,epsin,ubiquitin,phosphorylation

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