Does the Antisecretory Peptide AF-16 modulate fluid balance and inflammation in experimental peritonitis induced sepsis?

Annelie Barrueta Tenhunen, Jaap van der Heijden,Ivan Blokhin,Fabrizia Massaro,Hans Arne Hansson, Ricardo Feinstein,Anders Larsson,Jyrki Tenhunen

biorxiv（2020）

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摘要

No differences between the groups were observed regarding hemodynamics, fluid balance, lung mechanics, gas exchange or histology. This experimental study suggests that AF-16 does not modulate sepsis symptoms in peritonitis induced sepsis.

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关键词

Resuscitation,Fluid transport,Sepsis,Peritonitis,Intensive care,Hemodynamics,Mean arterial pressure,Inflammation,Anesthesia,Medicine

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