Oxidised phosphatidylcholines induce multiple functional defects in airway epithelial cells

In summary, we have identified OxPC as a bioactive model that significantly impairs multiple facets of epithelial cell function, consistent with pathological features of asthmatic epithelium. Further characterisation of the mechanisms by which OxPC affect epithelial cells could yield new insights into how oxidative stress contributes to the pathogenesis of airway disease.