Search
ChatPaper
AI Writing
analysis
Analysis
编组
Open Data
more
More
RankingsMust ReadingJournal&ConferenceAI TRAI HistoryMaster Reading TreeXiaomai's Star TalentsTrajectoryTalentNDI TrackerOpenAI sign Language
VIPCreated with Sketch.

PINK1 Regulates Dopamine and Lipids at Mitochondria to Maintain Synapses and Neuronal Function

Christine Bus,Sven Geisler,Marita Feldkaemper,Hector Flores-Romero,Anna Schaedler,Katharina Zittlau,Maria Zarani,Betül Uysal,Nicolas Casadei,Petra Fallier-Becker,Lisa Schwarz,Jos F. Brouwers,Henner Koch,Aslihan Ugun-Klusek,Klaudia Maruszczak,Daniela M. Vogt Weisenhorn,Wolfgang Wurst, Benjamin Schmidt,Gerard Martens,Britta Brügger,Doron Rapaport,Ana Garcia,Boris Macek,Rejko Krüger,Thomas Gasser,Philipp Kahle,Julia C. Fitzgerald

biorxiv（2019）

Cited 1|Views8
No score
Abstract
We suggest a novel mechanism for PINK1 pathogenicity in Parkinson’s disease in addition to but not exclusive of mitophagy. We also provide a basis for potential therapeutics by showing that low doses of the cholesterol depleting drug ß-cyclodextrin reverse PINK1-specific phenotypes.
More
Translated text
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined