The expanded BXD family of mice: A cohort for experimental systems genetics and precision medicine

David G. Ashbrook,Danny Arends,Pjotr Prins,Megan K. Mulligan,Suheeta Roy,Evan G. Williams,Cathleen M. Lutz,Alicia Valenzuela,Casey J. Bohl,Jesse F. Ingels,Melinda S. McCarty,Arthur G. Centeno,Reinmar Hager,Johan Auwerx,Saunak Sen,Lu Lu,Robert W. Williams

biorxiv（2019）

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摘要

The BXD family is an enduring, collaborative, and replicable resource to test causal and mechanistic links between genomes and phenomes at many stages and under a wide variety of treatments and interventions.

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关键词

Systems genetics,QTL,mapping resolution,power calculation,PheWAS,experimental precision medicine,recombinant inbred strain,mouse

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