Observation on the Effect of Sedative and Analgesic Drugs on Patients with Severe Craniocerebral Injury and Analysis of Nursing Effect

To analyze the curative effect and nursing effect of sedative and analgesic drugs on severe craniocerebral injury. From May 2016 to August 2018, 86 patients with severe craniocerebral injury were admitted in the Department of Severe Medicine of our hospital. According to different sedation and analgesia schemes, the patients were divided into two groups, namely the 42-case combined group and the 44-case conventional group. The patients in the conventional group were given routine analgesia and sedation nursing, and the patients in the combined group were given sedation and analgesia therapy and targeted nursing schemes with midazolam and sufentanil The sedative effect on the patients at 12h, 24h, 36h and 72h after treatment, the analgesic effect on the patients at 1H, 3H and 12h before and after treatment, and the incidence of adverse reactions during the treatment of the two groups were compared, and the satisfaction of the patients with nursing care during hospitalization was evaluated. The scores of Ramsay at 24h, 36h and 72h in the combined group were significantly lower than that in the conventional group (P < 0.05), the scores of Ramsay at all time points in the combined group were lower than that in the conventional group (P < 0.01), and the scores of Ramsay at 24h, 36h and 72h in the conventional group were significantly higher than that at 12h (P < 0.05); the cpot scores of the combined group at 1H, 3H and 12h after treatment were lower than that before and that in the conventional group (P < 0.05). The incidence of adverse reactions was 14.29% in the combined group and 20.45% in the conventional group. There was no significant difference between the two groups (P > 0.05). The nursing satisfaction in the combined group (95.24%) was significantly higher than that in the conventional group (77.27%). The difference between the two groups was statistically significant (P < 0.05). Midazolam combined with sufentanil has a significant effect on sedation and analgesia in patients with severe craniocerebral injury. Strengthened nursing in the course of treatment can reduce the occurrence of adverse events and improve nursing satisfaction.