HESC-derived sensory neurons reveal an unexpected role for PIEZO2 in nociceptor mechanotransduction

Katrin Schrenk-Siemens,Jörg Pohle,Charlotte Rostock,Muad Abd El Hay,Ruby M. Lam,Marcin Szczot,Shiying Lu,Alexander T. Chesler,Jan Siemens

biorxiv（2019）

引用 4|浏览15

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摘要

Surprisingly, all of the generated subtypes show mechano-nociceptive characteristics and, quite unexpectedly, loss of mechanotransduction in the absence of PIEZO2.

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