Liraglutide in combination with human umbilical cord mesenchymal stem cell could improve liver lesions by modulating TLR4/NF-kB inflammatory pathway and oxidative stress in T2DM/NAFLD rats.
Tissue and Cell(2020)
Abstract
•Liraglutide and hUC-MSCs can improve the regulation of T2DM with NAFLD.•The mechanism was related to the TLR4/NF-κB inflammatory pathway and oxidative stress.•There is no such basic research.
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Key words
Non-alcoholic fatty liver disease,Type 2 diabetes mellitus,Liraglutide,Human umbilical cord mesenchymal stem cell,TLR4/NF-κB,Oxidative stress
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